翻訳と辞書 Words near each other ・ Interleukin 23 ・ Interleukin 23 subunit alpha ・ Interleukin 24 ・ Interleukin 25 ・ Interleukin 26 ・ Interleukin 27 ・ Interleukin 27 receptor, alpha subunit ・ Interleukin 28 ・ Interleukin 28 receptor, alpha subunit ・ Interleukin 28B ・ Interleukin 29 ・ Interleukin 3 ・ Interleukin 30 ・ Interleukin 31 ・ Interleukin 32 ・ Interleukin 33 ・ Interleukin 34 ・ Interleukin 35 ・ Interleukin 36 receptor antagonist ・ Interleukin 37 ・ Interleukin 4 ・ Interleukin 5 ・ Interleukin 5 receptor alpha subunit ・ Interleukin 6 ・ Interleukin 7 ・ Interleukin 8 ・ Interleukin 8 receptor, alpha ・ Interleukin 8 receptor, beta ・ Interleukin 9 ・ Interleukin receptor Dictionary Lists mini英和辞書 mini和英辞書 Webster 1913 Latin-English FOLDOC Wikipedia English ウィキペディア

翻訳と辞書　辞書検索 [ 開発暫定版 ] スポンサード リンク Interleukin 33 ： ウィキペディア英語版 Interleukin 33 Interleukin 33 also known as IL-33 is a protein that in humans is encoded by the IL33 gene. IL-33 is a member of the IL-1 family that potently drives production of T helper-2 (Th2)-associated cytokines (e.g., IL-4). IL33 is a ligand for IL33R (IL1RL1), an IL-1 family receptor that is highly expressed on Th2 cells, mast cells and group 2 innate lymphocytes. IL-33 is expressed on a wide variety of cell types, including fibroblasts, mast cells, dendritic cells, macrophages, osteoblasts, endothelial cells, and epithelial cells. ==Function== Interleukin 33 (IL-33) is a cytokine belonging to the IL-1 superfamily. IL-33 induces helper T cells, mast cells, eosinophils and basophils to produce type 2 cytokines. This cytokine was previously named NF-HEV 'nuclear factor (NF) in high endothelial venules' (HEVs) since it was originally identified in these specialized cells. IL-33 mediates its biological effects by interacting with the receptors ST2 (also known as IL1RL1) and IL-1 Receptor Accessory Protein (IL1RAP), activating intracellular molecules in the NF-κB and MAP kinase signaling pathways that drive production of type 2 cytokines (e.g. IL-5 and IL-13) from polarized Th2 cells. The induction of type 2 cytokines by IL-33 ''in vivo'' is believed to induce the severe pathological changes observed in mucosal organs following administration of IL-33. 抄文引用元・出典: フリー百科事典『 ウィキペディア（Wikipedia）』 ■ウィキペディアで「Interleukin 33」の詳細全文を読む スポンサード リンク 翻訳と辞書 : 翻訳のためのインターネットリソース Copyright(C) kotoba.ne.jp 1997-2016. All Rights Reserved.